BAIT
RTP
9C4, CG10233, Dmel\CG10233, anon-83ABa, retin, uta, Dmel_CG10233
retinophilin
GO Process (1)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
KNI
CG4717, Dmel\CG4717, KNIRPS, Kn, NR0A1, knr, ri, Dmel_CG4717
knirps
GO Process (13)
GO Function (5)
GO Component (1)
Gene Ontology Biological Process
- branched duct epithelial cell fate determination, open tracheal system [TAS]
- dendrite morphogenesis [IMP]
- epidermis development [IMP]
- epithelial cell migration, open tracheal system [TAS]
- muscle organ development [IMP]
- negative regulation of transcription from RNA polymerase II promoter [TAS]
- negative regulation of transcription, DNA-templated [IDA, NAS]
- open tracheal system development [TAS]
- regulation of mitosis [IMP]
- regulation of transcription, DNA-templated [IGI, IMP]
- regulation of tube size, open tracheal system [TAS]
- trunk segmentation [TAS]
- zygotic determination of anterior/posterior axis, embryo [NAS, TAS]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [ISS, NAS]
- protein binding [IPI]
- repressing transcription factor binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA, ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [ISS, NAS]
- protein binding [IPI]
- repressing transcription factor binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA, ISS]
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID