BAIT
RCA1
152549_at, CG10800, CLD4, Dmel\CG10800, Emi1, FBXO5, P3300, S(rux)2A, l(2)03300, Dmel_CG10800
Regulator of cyclin A1
GO Process (7)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IMP]
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [ISM]
- eye-antennal disc morphogenesis [NAS]
- lateral inhibition [IMP]
- negative regulation of mitotic anaphase-promoting complex activity [IGI, IMP]
- neurogenesis [IMP]
- regulation of mitosis [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
SKPA
CG16983, Dmel\CG16983, EG:115C2.4, SKP1, Skp, anon-WO03040301.234, anon-WO03040301.236, anon-WO03040301.238, dSKP1, dSkp-1, dSkpA, l(1)G0037, l(1)G0058, l(1)G0109, l(1)G0389, spkA, Dmel_CG16983
CG16983 gene product from transcript CG16983-RD
GO Process (15)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- DNA endoreduplication [IMP]
- centrosome duplication [IMP]
- chromosome condensation [IMP]
- mitotic G2 DNA damage checkpoint [IGI]
- mitotic nuclear division [IMP]
- negative regulation of JNK cascade [IMP]
- negative regulation of apoptotic process [IGI, IMP]
- negative regulation of insulin receptor signaling pathway [IGI]
- negative regulation of synaptic growth at neuromuscular junction [IMP]
- neurogenesis [IMP]
- neuron remodeling [IMP]
- positive regulation of mitotic cell cycle [IMP]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [ISS]
- regulation of centrosome duplication [IMP]
- regulation of protein stability [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID