Co-purification

An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.

Publication

Thy-1 multimerization is correlated with neurite outgrowth.

Mahanthappa NK, Patterson PH

Thy-1 is abundantly expressed in the vertebrate nervous system. Perturbation studies in vitro suggest that Thy-1 inhibits neurite outgrowth and stabilizes neuronal processes (N. K. Mahanthappa and P. H. Patterson. (1992). Thy-1 involvement in neurite outgrowth: Perturbation by antibodies, phospholipase C, and mutation. Dev. Biol. 150,47-59). We here report that Thy-1 participates in several types of homophilic interactions, each with ... [more]

Dev. Biol. Mar. 01, 1992; 150(1);60-71 [Pubmed: 1347022]

Throughput

  • Low Throughput

Curated By

  • BioGRID