BAIT
TNPO1
IPO2, KPNB2, MIP, MIP1, TRN
transportin 1
GO Process (4)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
NUP98
ADIR2, NUP196, NUP96
nucleoporin 98kDa
GO Process (15)
GO Function (3)
GO Component (10)
Gene Ontology Biological Process
- DNA replication [IMP]
- carbohydrate metabolic process [TAS]
- cytokine-mediated signaling pathway [TAS]
- glucose transport [TAS]
- hexose transport [TAS]
- mitotic cell cycle [TAS]
- mitotic nuclear envelope disassembly [TAS]
- nuclear pore complex assembly [IMP]
- nuclear pore organization [NAS]
- nucleocytoplasmic transport [TAS]
- protein import into nucleus, docking [NAS]
- regulation of glucose transport [TAS]
- small molecule metabolic process [TAS]
- transmembrane transport [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Karyopherin beta2 mediates nuclear import of a mRNA binding protein.
We have cloned and sequenced cDNA for human karyopherin beta2, also known as transportin. In a solution binding assay, recombinant beta2 bound directly to recombinant nuclear mRNA-binding protein A1. Binding was inhibited by a peptide representing A1's previously characterized M9 nuclear localization sequence (NLS), but not by a peptide representing a classical NLS. As previously shown for karyopherin beta1, karyopherin ... [more]
Proc. Natl. Acad. Sci. U.S.A. May. 13, 1997; 94(10);5055-60 [Pubmed: 9144189]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| NUP98 TNPO1 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.119 | BioGRID | 1273431 |
Curated By
- BioGRID