Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

MICAL, a novel CasL interacting molecule, associates with vimentin.

Suzuki T, Nakamoto T, Ogawa S, Seo S, Matsumura T, Tachibana K, Morimoto C, Hirai H

CasL/HEF1 belongs to the p130(Cas) family. It is tyrosine-phosphorylated following beta(1) integrin and/or T cell receptor stimulation and is thus considered to be important for immunological reactions. CasL has several structural motifs such as an SH3 domain and a substrate domain and interacts with many molecules through these motifs. To obtain more insights on the CasL-mediated signal transduction, we sought ... [more]

J. Biol. Chem. Apr. 26, 2002; 277(17);14933-41 [Pubmed: 11827972]

Throughput

  • Low Throughput

Curated By

  • BioGRID