TRAK2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
OGT
Gene Ontology Biological Process
- apoptotic process [ISO, ISS]
- cellular response to glucose stimulus [IMP]
- cellular response to insulin stimulus [IEP]
- cellular response to lipopolysaccharide [IMP]
- cellular response to retinoic acid [ISO]
- cellular response to toxic substance [IEP]
- circadian regulation of gene expression [ISO, ISS]
- forebrain development [IEP]
- glucosamine metabolic process [IDA, IMP]
- histone H3-K4 trimethylation [ISO, ISS]
- histone H4-K16 acetylation [ISO, ISS]
- histone H4-K5 acetylation [ISO, ISS]
- histone H4-K8 acetylation [ISO, ISS]
- intracellular distribution of mitochondria [IMP]
- negative regulation of cell death [IMP]
- negative regulation of cellular response to hypoxia [IMP]
- negative regulation of peptidyl-serine phosphorylation [IMP]
- negative regulation of peptidyl-threonine phosphorylation [IMP]
- negative regulation of protein phosphorylation [IMP]
- negative regulation of protein targeting to membrane [IMP]
- negative regulation of protein ubiquitination [ISO, ISS]
- phosphatidylinositol-mediated signaling [ISO, ISS]
- positive regulation of catalytic activity [ISO]
- positive regulation of cell size [IMP]
- positive regulation of gene expression [IMP]
- positive regulation of granulocyte differentiation [ISO]
- positive regulation of histone H3-K27 methylation [ISO, ISS]
- positive regulation of histone H3-K4 methylation [ISO]
- positive regulation of protein localization to nucleus [IMP]
- positive regulation of protein phosphorylation [IMP]
- positive regulation of proteolysis [ISO, ISS]
- positive regulation of reactive oxygen species biosynthetic process [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO, ISS]
- protein O-linked glycosylation [IDA, IMP, ISO]
- protein heterotrimerization [IDA]
- protein homotrimerization [IDA]
- regulation of Rac protein signal transduction [ISO]
- regulation of gluconeogenesis involved in cellular glucose homeostasis [ISO, ISS]
- regulation of glycolytic process [ISO, ISS]
- regulation of insulin receptor signaling pathway [ISO]
- response to insulin [ISO]
Gene Ontology Molecular Function- enzyme activator activity [ISO]
- histone acetyltransferase activity (H4-K16 specific) [ISO, ISS]
- histone acetyltransferase activity (H4-K5 specific) [ISO, ISS]
- histone acetyltransferase activity (H4-K8 specific) [ISO, ISS]
- monosaccharide binding [IDA]
- peptide binding [IDA]
- phosphatidylinositol-3,4,5-trisphosphate binding [ISO, ISS]
- protein N-acetylglucosaminyltransferase activity [IDA, ISO]
- protein O-GlcNAc transferase activity [ISO, ISS]
- protein binding [IPI]
- protein domain specific binding [IPI]
- transcription factor binding [IPI]
- enzyme activator activity [ISO]
- histone acetyltransferase activity (H4-K16 specific) [ISO, ISS]
- histone acetyltransferase activity (H4-K5 specific) [ISO, ISS]
- histone acetyltransferase activity (H4-K8 specific) [ISO, ISS]
- monosaccharide binding [IDA]
- peptide binding [IDA]
- phosphatidylinositol-3,4,5-trisphosphate binding [ISO, ISS]
- protein N-acetylglucosaminyltransferase activity [IDA, ISO]
- protein O-GlcNAc transferase activity [ISO, ISS]
- protein binding [IPI]
- protein domain specific binding [IPI]
- transcription factor binding [IPI]
Gene Ontology Cellular Component
- MLL5-L complex [ISO]
- cytoplasm [IDA, ISO]
- cytosol [IDA, ISO]
- euchromatin [IDA]
- histone acetyltransferase complex [ISO, ISS]
- microtubule organizing center [ISO]
- mitochondrion [IDA]
- neuron projection [IDA]
- neuronal cell body [IDA]
- nucleoplasm [ISO]
- nucleus [IDA, ISO]
- plasma membrane [ISO, ISS]
- zymogen granule [IDA]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Identification and cloning of a novel family of coiled-coil domain proteins that interact with O-GlcNAc transferase.
The abundant and dynamic post-translational modification of nuclear and cytosolic proteins by beta-O-linked N-acetylglucosamine (O-GlcNAc) is catalyzed by O-GlcNAc transferase (OGT). Here we used the yeast two-hybrid approach to identify and isolate GABA(A) receptor-associated protein, GRIF-1 (Beck, M., Brickley, K., Wilkinson, H. L., Sharma, S., Smith, M., Chazot, P. L., Pollard, S., and Stephenson, F. A. (2002) J. Biol. Chem. ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| OGT TRAK2 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - | |
| OGT TRAK2 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID