BAIT
GRIP1
GRIP
glutamate receptor interacting protein 1
GO Process (4)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NUMBL
CAG3A, CTG3a, NBL, NUMB-R, NUMBLIKE, NUMBR, TNRC23
numb homolog (Drosophila)-like
GO Process (6)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex.
The PDZ domain-containing proteins, such as PSD-95 and GRIP, have been suggested to be involved in the targeting of glutamate receptors, a process that plays a critical role in the efficiency of synaptic transmission and plasticity. To address the molecular mechanisms underlying AMPA receptor synaptic localization, we have identified several GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within ... [more]
Neuron Jun. 01, 2000; 26(3);603-17 [Pubmed: 10896157]
Throughput
- Low Throughput
Curated By
- BioGRID