BAIT
PXN
hCG_1778014
paxillin
GO Process (9)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- cell adhesion [NAS]
- cell junction assembly [TAS]
- cellular response to reactive oxygen species [IEP]
- epidermal growth factor receptor signaling pathway [TAS]
- growth hormone receptor signaling pathway [IDA]
- muscle contraction [TAS]
- signal complex assembly [TAS]
- signal transduction [TAS]
- transforming growth factor beta receptor signaling pathway [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
REPS2
POB1, RP23-436I3.2
RALBP1 associated Eps domain containing protein 2
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Interaction of POB1, a downstream molecule of small G protein Ral, with PAG2, a paxillin-binding protein, is involved in cell migration.
POB1 was previously identified as a RalBP1-binding protein. POB1 and RalBP1 function downstream of small G protein Ral and regulate receptor-mediated endocytosis. To look for additional functions of POB1, we screened for POB1-binding proteins using a yeast two-hybrid method and found that POB1 interacts with mouse ASAP1, which is a human PAG2 homolog. PAG2 is a paxillin-associated protein with ADP-ribosylation ... [more]
J. Biol. Chem. Oct. 11, 2002; 277(41);38618-26 [Pubmed: 12149250]
Throughput
- Low Throughput
Curated By
- BioGRID