Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex.

Jo K, Derin R, Li M, Bredt DS

Protein assembly at the postsynaptic density (PSD) of neuronal synapses is mediated in part by protein interactions with PSD-95/discs large/zona occludens-1 (PDZ) motifs. Here, we identify MALS-1, -2, -3, a family of small synaptic proteins containing little more than a single PDZ domain. MALS-1, -2, and -3 are mammalian homologs LIN-7, a Caenorhabditis elegans protein essential for vulval development. In ... [more]

J. Neurosci. Jun. 01, 1999; 19(11);4189-99 [Pubmed: 10341223]

Throughput

  • Low Throughput

Curated By

  • BioGRID