BAIT
KIF13A
RBKIN, bA500C11.2, RP11-500C11.2
kinesin family member 13A
GO Process (10)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- Golgi to plasma membrane protein transport [ISS]
- cargo loading into vesicle [IMP]
- cytokinesis [IMP]
- endosome to lysosome transport [IMP]
- intracellular protein transport [IMP]
- melanosome organization [IMP]
- metabolic process [IBA, ISS]
- microtubule-based movement [IBA]
- plus-end-directed vesicle transport along microtubule [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
AP1M1
AP47, CLAPM2, CLTNM, MU-1A
adaptor-related protein complex 1, mu 1 subunit
GO Process (7)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex.
Intracellular transport mediated by kinesin superfamily proteins (KIFs) is a highly regulated process. The molecular mechanism of KIFs binding to their respective cargoes remains unclear. We report that KIF13A is a novel plus end-directed microtubule-dependent motor protein and associates with beta 1-adaptin, a subunit of the AP-1 adaptor complex. The cargo vesicles of KIF13A contained AP-1 and mannnose-6-phosphate receptor (M6PR). ... [more]
Cell Nov. 10, 2000; 103(4);569-81 [Pubmed: 11106728]
Throughput
- Low Throughput
Curated By
- BioGRID