PREY

RAP1GAP

RAP1GA1, RAP1GAP1, RAP1GAPII, RAPGAP, RP11-63N8.1
RAP1 GTPase activating protein
Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talk.

Meng J, Glick JL, Polakis P, Casey PJ

G(z) is a member of the G(i) family of trimeric G proteins whose primary role in cell physiology is still unknown. In an ongoing effort to elucidate the cellular functions of G(z), the yeast two-hybrid system was employed to identify proteins that specifically interact with a mutationally activated form of Galpha(z). One of the molecules uncovered in this screen was ... [more]

J. Biol. Chem. Dec. 17, 1999; 274(51);36663-9 [Pubmed: 10593970]

Throughput

  • Low Throughput

Curated By

  • BioGRID