BAIT

CDK2

CDKN2, p33(CDK2)
cyclin-dependent kinase 2
Alzheimer's Disease Project
Cell Cycle - Senescence Project
Fanconi Anemia Project
Human Papilloma Virus (HPV) Project
Homo sapiens
PREY

MS4A3

CD20L, HTM4
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

Human HTm4 is a hematopoietic cell cycle regulator.

Donato JL, Ko J, Kutok JL, Cheng T, Shirakawa T, Mao XQ, Beach D, Scadden DT, Sayegh MH, Adra CN

Proper control of cell cycle progression is critical for the constant self-renewal, differentiation, and homeostasis of the hematopoietic system. Cells of all types share the common cell cycle regulators. The different expression patterns of common regulators, in a broad sense, define cell-type or lineage specificity. However, there remains the possibility of hematopoietic cell cycle regulators tailored to the demands of ... [more]

J. Clin. Invest. Jan. 01, 2002; 109(1);51-8 [Pubmed: 11781350]

Throughput

  • Low Throughput

Curated By

  • BioGRID