Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Phosphorylation and regulation of a Gq/11-coupled receptor by casein kinase 1alpha.

Budd DC, McDonald JE, Tobin AB

Agonist-mediated receptor phosphorylation by one or more of the members of the G-protein receptor kinase (GRK) family is an established model for G-protein-coupled receptor (GPCR) phosphorylation resulting in receptor desensitization. Our recent studies have, however, suggested that an alternative route to GPCR phosphorylation may be an operation involving casein kinase 1alpha (CK1alpha). In the current study we investigate the involvement ... [more]

J. Biol. Chem. Jun. 30, 2000; 275(26);19667-75 [Pubmed: 10777483]

Throughput

  • Low Throughput

Curated By

  • BioGRID