BAIT
SMO
CG11561, Dmel\CG11561, dSmo, Dmel_CG11561
smoothened
GO Process (33)
GO Function (7)
GO Component (9)
Gene Ontology Biological Process
- Bolwig's organ morphogenesis [IMP]
- adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [IMP]
- anterior/posterior lineage restriction, imaginal disc [TAS]
- axon extension involved in axon guidance [IBA]
- blastoderm segmentation [IMP]
- canonical Wnt signaling pathway [IBA]
- cardioblast differentiation [IBA]
- cerebellar cortex morphogenesis [IBA]
- ciliary receptor clustering involved in smoothened signaling pathway [IBA]
- determination of left/right symmetry [IBA]
- eye morphogenesis [IMP]
- eye-antennal disc morphogenesis [IGI]
- gonad development [IBA]
- heart morphogenesis [IBA]
- negative regulation of G1/S transition of mitotic cell cycle [IMP]
- negative regulation of Notch signaling pathway [IGI]
- negative regulation of apoptotic process [IBA]
- negative regulation of transcription from RNA polymerase II promoter [IBA]
- neuron fate commitment [IBA]
- neuron projection regeneration [IBA]
- ovarian follicle cell development [IMP]
- positive regulation of establishment of protein localization to plasma membrane [IDA]
- positive regulation of neuroblast proliferation [IBA]
- positive regulation of smoothened signaling pathway [IBA]
- positive regulation of transcription from RNA polymerase II promoter [IBA]
- regulation of apoptotic process [IGI]
- regulation of mitotic cell cycle [IMP]
- signal transduction [ISS]
- smoothened signaling pathway [IMP, NAS, TAS]
- smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [IBA]
- somatic stem cell maintenance [IMP]
- vasculogenesis [IBA]
- wing disc anterior/posterior pattern formation [TAS]
Gene Ontology Molecular Function
Drosophila melanogaster
PREY
CG17493
CG40016, Dmel\CG17493, Dmel_CG17493
CG17493 gene product from transcript CG17493-RB
GO Process (0)
GO Function (1)
GO Component (1)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID