Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin.

Haeseleer F, Sokal I, Verlinde CL, Erdjument-Bromage H, Tempst P, Pronin AN, Benovic JL, Fariss RN, Palczewski K

Five members of a novel Ca(2+)-binding protein subfamily (CaBP), with 46-58% sequence similarity to calmodulin (CaM), were identified in the vertebrate retina. Important differences between these Ca(2+)-binding proteins and CaM include alterations within their second EF-hand loop that render these motifs inactive in Ca(2+) coordination and the fact that their central alpha-helixes are extended by one alpha-helical turn. CaBP1 and ... [more]

J. Biol. Chem. Jan. 14, 2000; 275(2);1247-60 [Pubmed: 10625670]

Throughput

  • Low Throughput

Additional Notes

  • Not sure CaBP2 is human

Curated By

  • BioGRID