CD2
Gene Ontology Biological Process
- T cell activation [TAS]
- apoptotic process [TAS]
- blood coagulation [TAS]
- cell surface receptor signaling pathway [TAS]
- heterotypic cell-cell adhesion [IDA]
- leukocyte migration [TAS]
- membrane raft polarization [TAS]
- natural killer cell activation [NAS]
- positive regulation of interferon-gamma secretion [IDA]
- positive regulation of interleukin-8 secretion [IMP]
- positive regulation of myeloid dendritic cell activation [NAS]
- positive regulation of tumor necrosis factor production [IDA]
- regulation of T cell differentiation [NAS]
- single organismal cell-cell adhesion [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CD53
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The OX-44 molecule couples to signaling pathways and is associated with CD2 on rat T lymphocytes and a natural killer cell line.
The MRC OX-44 molecule, which is expressed on all peripheral leukocytes, identifies the subset of thymocytes capable of proliferating in response to alloantigens and lectins (Paterson, D.J., J.R. Green, W.A. Jefferies, M. Puklavec, and A.F. Williams. 1987. J. Exp. Med. 165:1). When we isolated monoclonal antibodies (mAbs) on the basis of their ability to activate the phosphatidylinositol signaling pathway in ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID