CD46
Gene Ontology Biological Process
- T cell mediated immunity [IMP]
- adaptive immune response [IC]
- innate immune response [TAS]
- interleukin-10 production [IDA]
- negative regulation of gene expression [IDA]
- positive regulation of T cell proliferation [IDA]
- positive regulation of gene expression [IMP]
- positive regulation of interleukin-10 production [IDA]
- positive regulation of memory T cell differentiation [IDA]
- positive regulation of regulatory T cell differentiation [IDA]
- positive regulation of transforming growth factor beta production [IDA]
- regulation of Notch signaling pathway [IDA]
- regulation of complement activation [TAS]
- sequestering of extracellular ligand from receptor [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
MSN
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Physical association of moesin and CD46 as a receptor complex for measles virus.
Recently, two cellular membrane proteins, the membrane cofactor protein CD46 and the membrane-organizing external spike protein, moesin, have been identified to be functionally associated with measles virus (MV) infectivity of cells. We investigated the functional consequences of binding of monoclonal antibodies to both molecules individually and combined on MV attachment, fusion, and plaque formation and the putative direct physical interaction ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID