ITPR1
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- activation of phospholipase C activity [TAS]
- blood coagulation [TAS]
- calcium ion transport [NAS]
- energy reserve metabolic process [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- innate immune response [TAS]
- inositol phosphate-mediated signaling [ISS, TAS]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [ISS]
- negative regulation of calcium-mediated signaling [IDA]
- neurotrophin TRK receptor signaling pathway [TAS]
- platelet activation [TAS]
- regulation of insulin secretion [TAS]
- release of sequestered calcium ion into cytosol [ISS]
- response to hypoxia [IDA]
- signal transduction [NAS, TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ITPR3
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- G-protein coupled receptor signaling pathway [ISS]
- activation of phospholipase C activity [TAS]
- blood coagulation [TAS]
- calcium ion transport into cytosol [ISS]
- energy reserve metabolic process [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- innate immune response [TAS]
- inositol phosphate-mediated signaling [IDA, ISS]
- neurotrophin TRK receptor signaling pathway [TAS]
- platelet activation [TAS]
- positive regulation of cytosolic calcium ion concentration [ISS]
- protein heterooligomerization [ISS]
- protein homooligomerization [ISS]
- regulation of insulin secretion [TAS]
- response to calcium ion [IDA]
- signal transduction [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical part of cell [ISS]
- brush border [ISS]
- cytoplasm [ISS]
- endoplasmic reticulum [ISS]
- endoplasmic reticulum membrane [IDA, ISS, TAS]
- integral component of plasma membrane [IDA]
- membrane [IDA]
- myelin sheath [ISS]
- neuronal cell body [ISS]
- nuclear outer membrane [ISS]
- plasma membrane [IDA]
- platelet dense tubular network membrane [TAS]
- receptor complex [IDA]
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Heteroligomers of type-I and type-III inositol trisphosphate receptors in WB rat liver epithelial cells.
We have previously shown that a 222-kDa polypeptide co-immunoprecipitates together with the type-I myoinositol 1,4,5-trisphosphate receptor (IP3R) in WB rat liver epithelial cell extracts, when the immunoprecipitation is carried out with a type-I isoform specific antibody (Joseph, S. K. (1994) J. Biol. Chem. 269, 5673-5679). Utilizing isoform-specific antibodies raised to unique sequences within the COOH-terminal region of IP3 receptors, we ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ITPR3 ITPR1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 3359017 |
Curated By
- BioGRID