BAIT
UCP2
BMIQ4, SLC25A8, UCPH
uncoupling protein 2 (mitochondrial, proton carrier)
GO Process (5)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
YWHAQ
14-3-3, 1C5, HS1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
GO Process (6)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Uncoupling proteins 2 and 3 interact with members of the 14.3.3 family.
Uncoupling proteins (UCPs) are members of the superfamily of the mitochondrial anion carrier proteins (MATP). Localized in the inner membrane of the organelle, they are postulated to be regulators of mitochondrial uncoupling. UCP2 and 3 may play an important role in the regulation of thermogenesis and, thus, on the resting metabolic rate in humans. To identify interacting proteins that may ... [more]
Eur. J. Biochem. May. 01, 2000; 267(9);2680-7 [Pubmed: 10785390]
Throughput
- Low Throughput
Curated By
- BioGRID