BAIT
MLX
MAD7, MXD7, TCFL4, bHLHd13
MLX, MAX dimerization protein
GO Process (6)
GO Function (8)
GO Component (2)
Gene Ontology Biological Process
- energy reserve metabolic process [TAS]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of cellular metabolic process [TAS]
- regulation of transcription, DNA-templated [NAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA, IMP]
- protein binding [IPI]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription factor binding [IPI]
- DNA binding [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA, IMP]
- protein binding [IPI]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription factor binding [IPI]
Homo sapiens
PREY
MXD1
BHLHC58, MAD, MAD1
MAX dimerization protein 1
GO Process (3)
GO Function (5)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- sequence-specific DNA binding transcription factor activity [TAS]
- transcription cofactor activity [TAS]
- transcription corepressor activity [TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- sequence-specific DNA binding transcription factor activity [TAS]
- transcription cofactor activity [TAS]
- transcription corepressor activity [TAS]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway?
The Myc proto-oncogene family members have been identified as the cellular homologs of the transforming oncogene of avian retroviruses. They encode central regulators of mammalian cell proliferation and apoptosis, and they associate with the bHLHZip protein Max to bind specific DNA sequences and regulate the expression of genes important for cell cycle progression. The other family members, Mad1, Mxi1, Mad3, ... [more]
Oncogene Jul. 06, 2000; 19(29);3266-77 [Pubmed: 10918583]
Throughput
- Low Throughput
Related interactions
Curated By
- BioGRID