BAIT
PDK1
1210, CG1201, CG1210, DSTPK61, Dmel\CG1210, PDK, PDK-1, PDK1/Pk61C, PK61C, Pk61C/PDK1, dPDK-1, dPDK1, Dmel_CG1210
Phosphoinositide-dependent kinase 1
GO Process (14)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- cell surface receptor signaling pathway [IGI]
- cellular response to DNA damage stimulus [IMP]
- imaginal disc-derived wing morphogenesis [IMP]
- insulin receptor signaling pathway [NAS]
- negative regulation of apoptotic process [IMP]
- oogenesis [TAS]
- positive regulation of cell growth [NAS]
- positive regulation of cell size [IGI, TAS]
- protein phosphorylation [IDA, ISS, NAS]
- regulation of cell growth [IMP]
- regulation of organ growth [IMP]
- sex differentiation [TAS]
- spermatogenesis [TAS]
- synaptic growth at neuromuscular junction [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
L(3)NEO38
BcDNA:SD16005, CG14725, CG31364, CG6930, Dmel\CG6930, anon-EST:fe2F4, anon2F4, Dmel_CG6930
lethal (3) neo38
GO Process (2)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID