BAIT
CG12179
Dmel\CG12179, EG:66A1.2, Dmel_CG12179
CG12179 gene product from transcript CG12179-RD
GO Process (0)
GO Function (0)
GO Component (0)
Drosophila melanogaster
PREY
DLG1
11, CG1725, CG1730, CPD, DLG, DLG-A, Discs-large, DlgA, DlgS97, Dmel\CG1725, Drodlg, PSD95, SAP97, anon-EST:Posey93, anon-WO03040301.258, anon-WO03040301.260, anon-WO03040301.268, d. lg.-1, dlg-1, l(1)10Bf, l(1)G0276, l(1)G0342, l(1)G0456, l(1)G19, l(1)L11, l(1)bwn, l(1)d.lg-1, l(1)d.lg.-1, l(1)discs large, l(1)dlg, l(1)dlg-1, l(1)dlg1, l(1)l.pr.-2, l(1)lpr-2, misb, Dmel_CG1725
discs large 1
GO Process (32)
GO Function (4)
GO Component (18)
Gene Ontology Biological Process
- asymmetric protein localization [IMP, TAS]
- asymmetric protein localization involved in cell fate determination [TAS]
- basal protein localization [IMP, NAS]
- cell proliferation [TAS]
- cytoskeleton organization [NAS]
- dorsal closure [NAS, TAS]
- establishment of mitotic spindle orientation [IGI]
- establishment of spindle orientation [IMP]
- establishment or maintenance of epithelial cell apical/basal polarity [NAS, TAS]
- establishment or maintenance of neuroblast polarity [TAS]
- establishment or maintenance of polarity of embryonic epithelium [TAS]
- establishment or maintenance of polarity of follicular epithelium [IGI]
- establishment or maintenance of polarity of larval imaginal disc epithelium [NAS, TAS]
- gravitaxis [IMP]
- locomotor rhythm [IMP]
- male courtship behavior [IMP]
- mating behavior [IMP]
- morphogenesis of a polarized epithelium [TAS]
- morphogenesis of an epithelium [TAS]
- morphogenesis of follicular epithelium [IMP]
- morphogenesis of larval imaginal disc epithelium [TAS]
- negative regulation of cell proliferation [TAS]
- nervous system development [IMP]
- positive phototaxis [IMP]
- positive regulation of synaptic growth at neuromuscular junction [IMP]
- protein localization [IMP, TAS]
- regulation of border follicle cell delamination [TAS]
- regulation of cell cycle [NAS]
- regulation of cell proliferation [TAS]
- septate junction assembly [TAS]
- synaptic growth at neuromuscular junction [IMP]
- synaptic transmission [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical cortex [IDA]
- apicolateral plasma membrane [IDA]
- basolateral plasma membrane [TAS]
- cell cortex [IDA]
- cytoskeleton [NAS]
- lateral plasma membrane [IDA]
- membrane [TAS]
- neuromuscular junction [IDA]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA, IMP, NAS]
- postsynaptic membrane [IDA]
- presynaptic membrane [IDA]
- septate junction [NAS, TAS]
- smooth septate junction [IDA]
- synapse [IDA, TAS]
- terminal bouton [IDA]
- type I terminal bouton [IDA]
- type Ib terminal bouton [IDA]
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID