BAIT

DTX3

RNF154, deltex3
deltex 3, E3 ubiquitin ligase
UPS Project
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

RRBP1

ES/130, ES130, RRp, hES, RP11-462D18.3
ribosome binding protein 1
GO Process (2)
GO Function (2)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.

Wang L, Huang Y, Liu C, Guo M, Ma Z, He J, Wang A, Sun X, Liu Z

Background: Papillary thyroid carcinoma (PTC) is one of the most common endocrine malignant tumors. Poor prognoses such as high recurrence rate always appear in PTC patients with cervical lymph node metastasis. The process of ubiquitination plays important roles in PTC. As ubiquitin E3 ligases, Deltex (DTX) family proteins were reported to associate with multiple cancers. However, functions and mechanisms of ... [more]

J Cancer Jan. 07, 2021; 12(3);860-873 [Pubmed: 33403043]

Throughput

  • Low Throughput

Curated By

  • BioGRID