BAIT
DTX3
RNF154, deltex3
deltex 3, E3 ubiquitin ligase
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
RBMX
HNRNPG, HNRPG, RBMXP1, RBMXRT, RNMX, hnRNP-G, RP11-1114A5.1
RNA binding motif protein, X-linked
GO Process (12)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- RNA splicing [TAS]
- cellular response to interleukin-1 [IDA]
- gene expression [TAS]
- mRNA splicing, via spliceosome [IC, TAS]
- membrane protein ectodomain proteolysis [IDA]
- negative regulation of mRNA splicing, via spliceosome [ISS]
- osteoblast differentiation [IDA]
- positive regulation of mRNA splicing, via spliceosome [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- protein homooligomerization [ISS]
- regulation of alternative mRNA splicing, via spliceosome [IDA]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.
Background: Papillary thyroid carcinoma (PTC) is one of the most common endocrine malignant tumors. Poor prognoses such as high recurrence rate always appear in PTC patients with cervical lymph node metastasis. The process of ubiquitination plays important roles in PTC. As ubiquitin E3 ligases, Deltex (DTX) family proteins were reported to associate with multiple cancers. However, functions and mechanisms of ... [more]
J Cancer Jan. 07, 2021; 12(3);860-873 [Pubmed: 33403043]
Throughput
- Low Throughput
Curated By
- BioGRID