BAIT
RALGPS2
1810020P17Rik, 2210408F11Rik, 4921528G01Rik, 9130014M22Rik, AU043409, AW046161
Ral GEF with PH domain and SH3 binding motif 2
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY
RALA
3010001O15Rik, AW322615, Ral, Rasl1, RP23-5P19.1
v-ral simian leukemia viral oncogene homolog A (ras related)
GO Process (5)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Functional analysis of RalGPS2, a murine guanine nucleotide exchange factor for RalA GTPase.
RalGPS2 is a murine guanine nucleotide exchange factor of the RalGPS family; it contains a Cdc25-like GEF domain and does not exhibit a Ras-binding domain. The main characteristic of RalGPS2 is its pleckstrin homology (PH) domain, present at the C terminus, that preferentially binds phosphatidylinositol-4,5-biphosphate and in HEK 293 cells localized in membranes, causing ruffling and vesiculation. Moreover, RalGPS2 contains ... [more]
Exp Cell Res Jul. 01, 2007; 313(11);2293-307 [Pubmed: 17462626]
Throughput
- Low Throughput
Curated By
- BioGRID