BAIT

THRB

Nr1a2, T3R[b], T3Rbeta, Thrb1, Thrb2, c-erbAbeta
thyroid hormone receptor beta
Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor ?1.

Wang W, Ledee D

Thyroid hormones (THs) play a critical role in the metabolic phenotype of the heart; and most of the effects involve transcriptional regulation via thyroid hormone receptors (TRs). TRs ability to form combinatorial complexes with an array of partners accounts for TRs physiological flexibility in modulating gene expression. To identify proteins that associate with TR?1 in the heart we performed a ... [more]

Biochem Biophys Res Commun Oct. 22, 2021; 576();15-21 [Pubmed: 34474245]

Throughput

  • High Throughput

Additional Notes

  • C57BL/6 male mouse - heart tissue

Curated By

  • BioGRID