BAIT
MAPT
DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU
microtubule-associated protein tau
GO Process (8)
GO Function (7)
GO Component (8)
Gene Ontology Biological Process
- apoptotic process [TAS]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- generation of neurons [NAS]
- microtubule cytoskeleton organization [IDA]
- positive regulation of axon extension [IDA]
- positive regulation of microtubule polymerization [IDA]
- regulation of autophagy [IGI]
- regulation of microtubule polymerization [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CNP
CNPase, Cnp-1, Cnp1, RP24-319D9.2
2',3'-cyclic nucleotide 3' phosphodiesterase
GO Process (6)
GO Function (2)
GO Component (17)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell projection [ISO]
- cytoplasm [IBA, ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- membrane [IDA, ISO]
- microtubule [ISO]
- microvillus [ISO]
- mitochondrial inner membrane [ISO]
- mitochondrial outer membrane [ISO]
- myelin sheath [IDA]
- myelin sheath abaxonal region [ISO]
- myelin sheath adaxonal region [ISO]
- nucleoplasm [ISO]
- nucleus [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [ISO]
- pseudopodium [ISO]
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An N-terminal motif unique to primate tau enables differential protein-protein interactions.
Compared with other mammalian species, humans are particularly susceptible to tau-mediated neurodegenerative disorders. Differential interactions of the tau protein with other proteins are critical for mediating tau's physiological functions as well as tau-associated pathological processes. Primate tau harbors an 11-amino acid-long motif in its N-terminal region (residues 18-28), which is not present in non-primate species and whose function is unknown. ... [more]
J Biol Chem Dec. 09, 2017; 293(10);3710-3719 [Pubmed: 29382714]
Throughput
- High Throughput
Curated By
- BioGRID