PREY

ACO2

Aco-2, Aco3, D10Wsu183e
aconitase 2, mitochondrial
GO Process (3)
GO Function (4)
GO Component (3)
Mus musculus

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

An N-terminal motif unique to primate tau enables differential protein-protein interactions.

Stefanoska K, Volkerling A, Bertz J, Poljak A, Ke YD, Ittner LM, Ittner A

Compared with other mammalian species, humans are particularly susceptible to tau-mediated neurodegenerative disorders. Differential interactions of the tau protein with other proteins are critical for mediating tau's physiological functions as well as tau-associated pathological processes. Primate tau harbors an 11-amino acid-long motif in its N-terminal region (residues 18-28), which is not present in non-primate species and whose function is unknown. ... [more]

J Biol Chem Dec. 09, 2017; 293(10);3710-3719 [Pubmed: 29382714]

Throughput

  • High Throughput

Curated By

  • BioGRID