BAIT

EP300

KAT3B, RSTS2, p300, RP1-85F18.1
E1A binding protein p300
GO Process (29)
GO Function (15)
GO Component (3)

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

Li X, Li S, Li B, Li Y, Aman S, Xia K, Yang Y, Ahmad B, Wu H

E74-like ETS transcription factor 5 (ELF5) is involved in a wide spectrum of biological processes, e.g., mammogenesis and tumor progression. We have identified a list of p300-interacting proteins in human breast cancer cells. Among these, ELF5 was found to interact with p300 via acetylation, and the potential acetylation sites were identified as K130, K134, K143, K197, K228, and K245. Furthermore, ... [more]

NPJ Precis Oncol Mar. 19, 2021; 5(1);20 [Pubmed: 33742100]

Throughput

  • Low Throughput

Curated By

  • BioGRID