BAIT
WIPI1
ATG18, ATG18A, WIPI49
WD repeat domain, phosphoinositide interacting 1
GO Process (11)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
- activation of signaling protein activity involved in unfolded protein response [TAS]
- autophagic vacuole assembly [IBA]
- autophagy [IEP]
- cellular protein metabolic process [TAS]
- cellular response to nitrogen starvation [IBA]
- endoplasmic reticulum unfolded protein response [TAS]
- mitochondrion degradation [IBA]
- nucleophagy [IBA]
- protein lipidation [IBA]
- protein localization to pre-autophagosomal structure [IBA]
- vesicle targeting, trans-Golgi to endosome [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ATG16L1
APG16L, ATG16A, ATG16L, IBD10, WDR30, hCG_1817841
autophagy related 16-like 1 (S. cerevisiae)
GO Process (3)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy.
Macroautophagy/autophagy is an intracellular degradation process that delivers cytosolic materials and/or damaged organelles to lysosomes. De novo synthesis of the autophagosome membrane occurs within a phosphatidylinositol-3-phosphate-rich region of the endoplasmic reticulum, and subsequent expansion is critical for cargo encapsulation. This process is complex, especially in mammals, with many regulatory factors. In this study, by utilizing PRKN (parkin RBR E3 ubiquitin ... [more]
Autophagy Dec. 01, 2020; 17(8);2011-2036 [Pubmed: 33499712]
Throughput
- Low Throughput
Curated By
- BioGRID