BAIT
FSCN1
FAN1, HSN, SNL, p55
fascin actin-bundling protein 1
GO Process (5)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RFC4
A1, RFC37
replication factor C (activator 1) 4, 37kDa
GO Process (11)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- DNA repair [TAS]
- DNA replication [TAS]
- DNA strand elongation involved in DNA replication [TAS]
- mitotic cell cycle [TAS]
- nucleotide-excision repair [TAS]
- nucleotide-excision repair, DNA gap filling [TAS]
- telomere maintenance [TAS]
- telomere maintenance via recombination [TAS]
- telomere maintenance via semi-conservative replication [TAS]
- transcription-coupled nucleotide-excision repair [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Mass spectrometry-based proteomic analysis of FSCN1-interacting proteins in laryngeal squamous cell carcinoma cells.
Fascin actin-bundling protein 1 (FSCN1) is an evolutionarily conserved actin-bundling protein that plays a critical role in cell migration, motility, adhesion, and cellular interactions. Although multiple clinical studies have implicated the expression of FSCN1 in laryngeal squamous cell carcinoma (LSCC) progression, the precise mechanism of FSCN1 in the process has not been clearly elucidated. To define FSCN1 function, we characterized ... [more]
IUBMB Life Dec. 01, 2018; 71(11);1771-1784 [Pubmed: 31298480]
Throughput
- Low Throughput
Curated By
- BioGRID