BAIT
FSCN1
FAN1, HSN, SNL, p55
fascin actin-bundling protein 1
GO Process (5)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ELP3
KAT9
elongator acetyltransferase complex subunit 3
GO Process (9)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- central nervous system development [ISS]
- chromatin organization [TAS]
- histone H3 acetylation [IDA]
- histone H4 acetylation [IDA]
- neuron migration [ISS]
- positive regulation of cell migration [ISS]
- regulation of protein kinase activity [IDA]
- regulation of transcription from RNA polymerase II promoter [IDA, TAS]
- transcription elongation from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Mass spectrometry-based proteomic analysis of FSCN1-interacting proteins in laryngeal squamous cell carcinoma cells.
Fascin actin-bundling protein 1 (FSCN1) is an evolutionarily conserved actin-bundling protein that plays a critical role in cell migration, motility, adhesion, and cellular interactions. Although multiple clinical studies have implicated the expression of FSCN1 in laryngeal squamous cell carcinoma (LSCC) progression, the precise mechanism of FSCN1 in the process has not been clearly elucidated. To define FSCN1 function, we characterized ... [more]
IUBMB Life Dec. 01, 2018; 71(11);1771-1784 [Pubmed: 31298480]
Throughput
- Low Throughput
Curated By
- BioGRID