BAIT
ZRANB1
TRABID, RP11-298J20.4
zinc finger, RAN-binding domain containing 1
GO Process (8)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- cell migration [IMP]
- cytoskeleton organization [IMP]
- positive regulation of Wnt signaling pathway [IMP]
- protein K29-linked deubiquitination [IDA]
- protein K33-linked deubiquitination [IDA]
- protein K63-linked deubiquitination [IDA, IMP]
- protein deubiquitination involved in ubiquitin-dependent protein catabolic process [IMP]
- regulation of cell morphogenesis [IMP]
Gene Ontology Molecular Function
Homo sapiens
PREY
SIPA1L1
E6TP1
signal-induced proliferation-associated 1 like 1
GO Process (7)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.
Ubiquitin is a versatile posttranslational modification, which is covalently attached to protein targets either as a single moiety or as a ubiquitin chain. In contrast to K48 and K63-linked chains, which have been extensively studied, the regulation and function of most atypical ubiquitin chains are only starting to emerge. The deubiquitinase TRABID/ZRANB1 is tuned for the recognition and cleavage of ... [more]
J Biol Chem Apr. 16, 2021; 296();100246 [Pubmed: 33853758]
Throughput
- Low Throughput
Curated By
- BioGRID