BAIT
LSM5
YER146W
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
GO Process (5)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
PRDX1
MSP23, NkefA, OSF-3, OSF3, PAG, Paga, PrdxI, PrxI, TDX2, TPxA, Tdpx2, prx1, RP23-177C18.2
peroxiredoxin 1
GO Process (10)
GO Function (8)
GO Component (11)
Gene Ontology Biological Process
- cell proliferation [IMP]
- erythrocyte homeostasis [IMP]
- hydrogen peroxide catabolic process [ISO]
- natural killer cell mediated cytotoxicity [IMP]
- oxidation-reduction process [ISO]
- regulation of NF-kappaB import into nucleus [IMP]
- regulation of stress-activated MAPK cascade [IMP]
- removal of superoxide radicals [IMP]
- response to oxidative stress [IDA, IMP]
- response to reactive oxygen species [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.
RNA-binding proteins (RBPs) are crucial factors of post-transcriptional gene regulation and their modes of action are intensely investigated. At the center of attention are RNA motifs that guide where RBPs bind. However, sequence motifs are often poor predictors of RBP-RNA interactions in vivo. It is hence believed that many RBPs recognize RNAs as complexes, to increase specificity and regulatory possibilities. ... [more]
Nucleic Acids Res Dec. 09, 2020; 49(12);6702-6721 [Pubmed: 34133714]
Throughput
- High Throughput
Additional Notes
- Included protein pairs with sumIS score >= 7.1
Curated By
- BioGRID