BAIT
ELAVL1
2410055N02Rik, HUR, Hua, W91709
ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
GO Process (5)
GO Function (8)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
RBM38
Rnpc1, Seb4, Seb4l, RP23-368M21.3
RNA binding motif protein 38
GO Process (6)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- 3'-UTR-mediated mRNA stabilization [ISO]
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [ISO]
- DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [ISO]
- negative regulation of cell proliferation [ISO]
- regulation of RNA splicing [ISO]
- regulation of myotube differentiation [IDA]
Gene Ontology Molecular Function
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.
RNA-binding proteins (RBPs) are crucial factors of post-transcriptional gene regulation and their modes of action are intensely investigated. At the center of attention are RNA motifs that guide where RBPs bind. However, sequence motifs are often poor predictors of RBP-RNA interactions in vivo. It is hence believed that many RBPs recognize RNAs as complexes, to increase specificity and regulatory possibilities. ... [more]
Nucleic Acids Res Dec. 09, 2020; 49(12);6702-6721 [Pubmed: 34133714]
Throughput
- High Throughput
Additional Notes
- Included protein pairs with sumIS score >= 7.1
Curated By
- BioGRID