BAIT
RPS3
D7Ertd795e, Rs_3
ribosomal protein S3
GO Process (7)
GO Function (11)
GO Component (12)
Gene Ontology Biological Process
- DNA catabolic process, endonucleolytic [IBA, ISO]
- DNA repair [IBA]
- cytoplasmic translation [IBA]
- negative regulation of DNA repair [ISO]
- positive regulation of DNA N-glycosylase activity [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of apoptotic signaling pathway [ISO]
Gene Ontology Molecular Function- DNA-(apurinic or apyrimidinic site) lyase activity [ISO]
- NF-kappaB binding [ISO]
- damaged DNA binding [IBA, ISO]
- enzyme binding [ISO]
- mRNA binding [ISO]
- oxidized purine nucleobase lesion DNA N-glycosylase activity [IBA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein kinase A binding [ISO]
- protein kinase binding [ISO]
- structural constituent of ribosome [IBA, ISO]
- DNA-(apurinic or apyrimidinic site) lyase activity [ISO]
- NF-kappaB binding [ISO]
- damaged DNA binding [IBA, ISO]
- enzyme binding [ISO]
- mRNA binding [ISO]
- oxidized purine nucleobase lesion DNA N-glycosylase activity [IBA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein kinase A binding [ISO]
- protein kinase binding [ISO]
- structural constituent of ribosome [IBA, ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
POLRMT
1110018N15Rik, 4932416K13
polymerase (RNA) mitochondrial (DNA directed)
GO Process (1)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.
RNA-binding proteins (RBPs) are crucial factors of post-transcriptional gene regulation and their modes of action are intensely investigated. At the center of attention are RNA motifs that guide where RBPs bind. However, sequence motifs are often poor predictors of RBP-RNA interactions in vivo. It is hence believed that many RBPs recognize RNAs as complexes, to increase specificity and regulatory possibilities. ... [more]
Nucleic Acids Res Dec. 09, 2020; 49(12);6702-6721 [Pubmed: 34133714]
Throughput
- High Throughput
Additional Notes
- Included protein pairs with sumIS score >= 7.1
Curated By
- BioGRID