BAIT
APLP2
AI790698, APLP-2
amyloid beta (A4) precursor-like protein 2
GO Process (12)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- cellular copper ion homeostasis [IMP]
- cholesterol metabolic process [IGI]
- embryo development [IGI]
- extracellular matrix organization [IGI]
- forebrain development [IGI]
- locomotory behavior [IGI]
- mating behavior [IGI]
- midbrain development [IGI]
- neuromuscular process controlling balance [IGI]
- regulation of epidermal growth factor-activated receptor activity [IGI]
- regulation of protein binding [IGI]
- suckling behavior [IGI]
Gene Ontology Molecular Function
Mus musculus
PREY
RHOA
Arha, Arha1, Arha2
ras homolog gene family, member A
GO Process (44)
GO Function (7)
GO Component (13)
Gene Ontology Biological Process
- GTP catabolic process [IDA, ISO]
- Rho protein signal transduction [TAS]
- actin cytoskeleton organization [IDA]
- androgen receptor signaling pathway [IDA]
- apical junction assembly [IDA, ISO]
- apolipoprotein A-I-mediated signaling pathway [ISO]
- cell adhesion [IMP]
- cell differentiation [IDA]
- cell morphogenesis [IGI]
- cell-matrix adhesion [IDA]
- cerebral cortex cell migration [IMP]
- cleavage furrow formation [ISO]
- cytoskeleton organization [IMP]
- forebrain radial glial cell differentiation [IMP]
- integrin-mediated signaling pathway [TAS]
- negative chemotaxis [ISO]
- negative regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- negative regulation of cell death [ISO]
- negative regulation of intracellular steroid hormone receptor signaling pathway [IDA]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of neuron differentiation [ISO]
- ossification involved in bone maturation [IMP]
- positive regulation of actin filament polymerization [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of cytokinesis [ISO]
- positive regulation of neuron apoptotic process [ISO]
- positive regulation of neuron differentiation [ISO]
- positive regulation of podosome assembly [IGI]
- positive regulation of smooth muscle contraction [ISO]
- positive regulation of stress fiber assembly [ISO]
- regulation of calcium ion transport [ISO]
- regulation of cell migration [ISO]
- regulation of dendrite development [ISO]
- regulation of neural precursor cell proliferation [IMP]
- regulation of neuron projection development [IDA]
- regulation of osteoblast proliferation [IMP]
- regulation of transcription from RNA polymerase II promoter [IDA]
- response to drug [ISO]
- skeletal muscle tissue development [IDA]
- spindle assembly involved in mitosis [ISO]
- stress fiber assembly [IDA]
- stress-activated protein kinase signaling cascade [ISO]
- trabecula morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The in vivo brain interactome of the amyloid precursor protein.
Despite intense research efforts, the physiological function and molecular environment of the amyloid precursor protein has remained enigmatic. Here we describe the application of time-controlled transcardiac perfusion cross-linking, a method for the in vivo mapping of protein interactions in intact tissue, to study the interactome of the amyloid precursor protein (APP). To gain insights into the specificity of reported protein ... [more]
Mol Cell Proteomics Jan. 01, 2008; 7(1);15-34 [Pubmed: 17934213]
Throughput
- Low Throughput
Curated By
- BioGRID