BAIT
ILDR2
2810478N18Rik, 3110063L10Rik, AI852300, D1Ertd471e, Dbsm1, ENSMUSG00000040612, Ll
immunoglobulin-like domain containing receptor 2
GO Process (5)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Mus musculus
PREY
SENP1
2310046A20Rik, D15Ertd528e, E330036L07Rik, suPr-2
SUMO1/sentrin specific peptidase 1
GO Process (7)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- activation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- apoptotic signaling pathway [ISO]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- protein desumoylation [IDA, IMP, ISO]
- proteolysis [IMP]
- regulation of definitive erythrocyte differentiation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
ILDR2 stabilization is regulated by its interaction with GRP78.
Ildr2 was initially identified as a genetic modifier of diabetes susceptibility in B6.DBA Lepob congenic mice, and was associated with decreased ?-cell replication rates, reduced ?-cell mass, and persistent mild hypoinsulinemic hyperglycemia. However, the molecular mechanisms of how the ILDR2 protein is involved in these effects are largely unknown. We sought to identify ILDR2-interacting proteins to further elucidate the molecular mechanisms underpinning ... [more]
Sci Rep Dec. 16, 2020; 11(1);8414 [Pubmed: 33863978]
Throughput
- Low Throughput
Curated By
- BioGRID