BAIT
NLRP7
CLR19.4, HYDM, NALP7, NOD12, PAN7, PYPAF3, XXbac-BCX195L8.11-001
NLR family, pyrin domain containing 7
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
NME1
AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1
NME/NM23 nucleoside diphosphate kinase 1
GO Process (8)
GO Function (9)
GO Component (6)
Gene Ontology Biological Process
- DNA catabolic process [IDA]
- negative regulation of cell proliferation [TAS]
- nucleobase-containing small molecule interconversion [TAS]
- nucleobase-containing small molecule metabolic process [TAS]
- positive regulation of DNA binding [IDA]
- positive regulation of epithelial cell proliferation [IMP]
- regulation of apoptotic process [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
NLRP7 deubiquitination by USP10 promotes tumor progression and tumor-associated macrophage polarization in colorectal cancer.
NOD-like receptors affect multiple stages of cancer progression in many malignancies. NACHT, LRR, and PYD domain-containing protein 7 (NLRP7) is a member of the NOD-like receptor family, although its role in tumorigenesis remains unclear. By analyzing clinical samples, we found that NLRP7 protein levels were upregulated in colorectal cancer (CRC). We proposed the hypothesis that a high level of NLRP7 ... [more]
J Exp Clin Cancer Res Apr. 10, 2021; 40(1);126 [Pubmed: 33838681]
Throughput
- Low Throughput
Curated By
- BioGRID