BAIT

NLRP7

CLR19.4, HYDM, NALP7, NOD12, PAN7, PYPAF3, XXbac-BCX195L8.11-001
NLR family, pyrin domain containing 7
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

DGCR8

C22orf12, DGCRK6, Gy1, pasha, LP4941
DGCR8 microprocessor complex subunit
GO Process (2)
GO Function (2)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

NLRP7 deubiquitination by USP10 promotes tumor progression and tumor-associated macrophage polarization in colorectal cancer.

Li B, Qi ZP, He DL, Chen ZH, Liu JY, Wong MW, Zhang JW, Xu EP, Shi Q, Cai SL, Sun D, Yao LQ, Zhou PH, Zhong YS

NOD-like receptors affect multiple stages of cancer progression in many malignancies. NACHT, LRR, and PYD domain-containing protein 7 (NLRP7) is a member of the NOD-like receptor family, although its role in tumorigenesis remains unclear. By analyzing clinical samples, we found that NLRP7 protein levels were upregulated in colorectal cancer (CRC). We proposed the hypothesis that a high level of NLRP7 ... [more]

J Exp Clin Cancer Res Apr. 10, 2021; 40(1);126 [Pubmed: 33838681]

Throughput

  • Low Throughput

Curated By

  • BioGRID