BAIT

KAT6A

MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220
K(lysine) acetyltransferase 6A
UPS Project
Homo sapiens
PREY

DBNL

ABP1, HIP-55, HIP55, SH3P7, PP5423
drebrin-like
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

KAT6A, a novel regulator of ?-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.

Liu W, Zhan Z, Zhang M, Sun B, Shi Q, Luo F, Zhang M, Zhang W, Hou Y, Xiao X, Li Y, Feng H

Background: Ovarian cancer is a fatal gynecologic malignancy that is found worldwide and exhibits an insidious onset and a lack of early warning symptoms. Despite ongoing studies, the mechanistic basis of the aggressive phenotypes of ovarian cancer remains unclear. Lysine acetyltransferase 6A (KAT6A) is a MYST-type histone acetyltransferase (HAT) enzyme identified as an oncogene in breast cancer, glioblastoma and leukemia. ... [more]

Theranostics May. 18, 2021; 11(13);6278-6292 [Pubmed: 33995658]

Throughput

  • Low Throughput

Curated By

  • BioGRID