BAIT
RL
12559, BcDNA:RE08694, CG12559, CG18732, CT34260, CT39192, D-ERK, DERK, DERK-A, DmERK-A, DmERKA, DmErk, DmMAPK, Dmel\CG12559, DpERK, Dsor2, E(sina)7, EK2-1, ERK, ERK-A, ERKA, EY2-2, Erk/Map kinase, Erk1, GroupII, MAP-k, MAPK, SEM, SR2-1, Su(Raf)2B, dm-dpERK, dp-ERK, dpERK1, dpMAPK, l(2)41Ac, l(2R)EMS45-39, pERK, pMAPK, rl/ERK, rl/MAPK, rll, Dmel_CG12559
rolled
GO Process (33)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- MAPK cascade [NAS]
- R7 cell development [TAS]
- adherens junction maintenance [IMP]
- anterior/posterior axis specification, embryo [TAS]
- behavioral response to ethanol [IMP]
- cellular response to DNA damage stimulus [IMP]
- cellular response to arsenic-containing substance [IDA]
- cellular response to cadmium ion [IDA]
- cellular response to reactive oxygen species [IDA]
- cellular response to starvation [IMP]
- epidermal growth factor receptor signaling pathway [NAS]
- gastrulation [NAS]
- heart development [NAS]
- imaginal disc-derived wing morphogenesis [IMP]
- imaginal disc-derived wing vein morphogenesis [IMP]
- imaginal disc-derived wing vein specification [IMP]
- metamorphosis [IMP]
- mitotic nuclear division [IMP]
- negative regulation of apoptotic process [NAS]
- negative regulation of macroautophagy [IMP]
- positive regulation of ERK1 and ERK2 cascade [IGI]
- positive regulation of Ras protein signal transduction [IGI]
- positive regulation of cell proliferation [IMP]
- positive regulation of photoreceptor cell differentiation [IMP]
- positive regulation of wound healing [IMP]
- protein phosphorylation [NAS, TAS]
- regulation of response to drug [IMP]
- regulation of synapse structure or activity [TAS]
- regulation of synaptic transmission [IMP]
- regulation of transcription, DNA-templated [TAS]
- sevenless signaling pathway [NAS]
- torso signaling pathway [NAS]
- transmembrane receptor protein tyrosine kinase signaling pathway [IMP]
Gene Ontology Molecular Function
Drosophila melanogaster
PREY
MEKK1
CG7717, D-MEKK1, DmMEKK1, Dmel\CG7717, MEKK, MEKK4, Mekk1/4, dMEKK, dMEKK1, dMEKK4, mekk1a, mekk1b, Dmel_CG7717
CG7717 gene product from transcript CG7717-RB
GO Process (14)
GO Function (3)
GO Component (0)
Gene Ontology Biological Process
- MAPK cascade [IDA]
- cellular hyperosmotic salinity response [IMP]
- cellular response to arsenic-containing substance [IMP]
- cellular response to cadmium ion [IMP]
- cellular response to heat [IDA, IMP]
- engulfment of apoptotic cell [IMP]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [IGI]
- mucosal immune response [IMP]
- negative regulation of heterochromatin assembly [IMP]
- positive regulation of JNK cascade [IMP]
- positive regulation of cell size [IGI, IMP]
- positive regulation of protein phosphorylation [IGI]
- protein phosphorylation [IDA, NAS, TAS]
- response to oxidative stress [IMP]
Gene Ontology Molecular Function
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID