MED18
Gene Ontology Molecular Function
Gene Ontology Cellular Component
G6PD
Gene Ontology Biological Process
- NADP metabolic process [IDA]
- NADPH regeneration [IMP]
- carbohydrate metabolic process [TAS]
- cellular response to oxidative stress [IMP]
- cholesterol biosynthetic process [IMP]
- cytokine production [IMP]
- erythrocyte maturation [IMP]
- glucose 6-phosphate metabolic process [IDA, IMP]
- glutathione metabolic process [IMP]
- lipid metabolic process [TAS]
- negative regulation of protein glutathionylation [IMP]
- oxidation-reduction process [IMP]
- pentose biosynthetic process [IDA]
- pentose-phosphate shunt [IDA, TAS]
- pentose-phosphate shunt, oxidative branch [IMP]
- ribose phosphate biosynthetic process [IMP]
- small molecule metabolic process [TAS]
- substantia nigra development [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Quantitative Score
- 0.480470423 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.480470423462653, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| MED18 G6PD | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9964 | BioGRID | 2236599 | |
| MED18 G6PD | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8843 | BioGRID | 3076831 |
Curated By
- BioGRID