POP4
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RBM4
Gene Ontology Biological Process
- IRES-dependent translational initiation [IDA]
- RNA processing [TAS]
- cap-independent translational initiation [IDA]
- circadian regulation of translation [ISS]
- entrainment of circadian clock by photoperiod [ISS]
- negative regulation of translation [IDA]
- negative regulation of translation in response to stress [IDA]
- negative regulation of translation involved in gene silencing by miRNA [IDA]
- negative regulation of translational initiation [IDA]
- positive regulation of muscle cell differentiation [IDA]
- regulation of alternative mRNA splicing, via spliceosome [IDA]
- regulation of nucleocytoplasmic transport [IDA]
- response to arsenic-containing substance [IDA]
- stress-activated MAPK cascade [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Quantitative Score
- 0.998784486 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.99878448621793, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RBM4 POP4 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9941 | BioGRID | 2238757 | |
| RBM4 POP4 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9935 | BioGRID | 3100845 |
Curated By
- BioGRID