BAIT
RAMP3
receptor (G protein-coupled) activity modifying protein 3
GO Process (9)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway involved in heart process [ISS]
- calcium ion transport [IDA]
- cellular response to estradiol stimulus [ISS]
- negative regulation of transcription, DNA-templated [IMP]
- positive regulation of establishment of protein localization to plasma membrane [IDA]
- positive regulation of receptor recycling [IDA]
- protein localization to plasma membrane [IDA]
- protein transport [IDA]
- receptor internalization [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
COX15
CEMCOX2
cytochrome c oxidase assembly homolog 15 (yeast)
GO Process (10)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- cellular respiration [IC]
- heme a biosynthetic process [IGI]
- heme biosynthetic process [TAS]
- hydrogen ion transmembrane transport [IGI, TAS]
- mitochondrial electron transport, cytochrome c to oxygen [IC]
- oxidation-reduction process [TAS]
- porphyrin-containing compound metabolic process [TAS]
- respiratory chain complex IV assembly [IMP]
- respiratory gaseous exchange [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Status: Pre-Publication Dataset
Quantitative Score
- 0.363738201 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.363738200763107, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Curated By
- BioGRID