SFRP2
Gene Ontology Biological Process
- cardiac left ventricle morphogenesis [IMP]
- cell-cell signaling [ISS]
- hematopoietic stem cell proliferation [ISS]
- negative regulation of Wnt signaling pathway [IDA]
- negative regulation of canonical Wnt signaling pathway [IDA]
- negative regulation of cell growth [IDA]
- negative regulation of cell migration [ISS]
- negative regulation of cell proliferation [IDA, IMP]
- negative regulation of dermatome development [ISS]
- negative regulation of epithelial cell proliferation [IDA]
- negative regulation of epithelial to mesenchymal transition [IDA]
- negative regulation of gene expression [ISS]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [ISS]
- negative regulation of peptidyl-tyrosine phosphorylation [ISS]
- negative regulation of transcription, DNA-templated [IDA]
- non-canonical Wnt signaling pathway [IBA]
- outflow tract morphogenesis [IMP]
- patterning of blood vessels [ISS]
- positive regulation of angiogenesis [ISS]
- positive regulation of apoptotic process [IMP]
- positive regulation of canonical Wnt signaling pathway [ISS]
- positive regulation of cell adhesion mediated by integrin [ISS]
- positive regulation of cell growth [ISS]
- positive regulation of cell proliferation [IDA]
- positive regulation of fat cell differentiation [IDA]
- positive regulation of peptidyl-serine phosphorylation [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- regulation of stem cell division [ISS]
- sclerotome development [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RANBP9
Gene Ontology Biological Process
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Quantitative Score
- 0.59974402 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.599744020372825, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SFRP2 RANBP9 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8136 | BioGRID | 1181073 |
Curated By
- BioGRID