PLIN5
Gene Ontology Biological Process
- lipid particle organization [ISS]
- negative regulation of fatty acid beta-oxidation [ISS]
- negative regulation of lipase activity [ISS]
- negative regulation of peroxisome proliferator activated receptor signaling pathway [ISS]
- negative regulation of reactive oxygen species metabolic process [ISS]
- negative regulation of triglyceride catabolic process [ISS]
- positive regulation of fatty acid beta-oxidation [ISS]
- positive regulation of lipase activity [ISS]
- positive regulation of lipid storage [ISS]
- positive regulation of sequestering of triglyceride [ISS]
- positive regulation of triglyceride biosynthetic process [ISS]
Gene Ontology Cellular Component
INPPL1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Quantitative Score
- 0.999966869 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.999966868568127, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PLIN5 INPPL1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9937 | BioGRID | 1196210 | |
| PLIN5 INPPL1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9762 | BioGRID | 2246144 | |
| PLIN5 INPPL1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9863 | BioGRID | 3121462 |
Curated By
- BioGRID