UGT1A1
Gene Ontology Biological Process
- bilirubin conjugation [TAS]
- cellular glucuronidation [IDA, NAS, TAS]
- cellular response to hormone stimulus [IBA]
- digestion [NAS]
- drug metabolic process [IC]
- estrogen metabolic process [TAS]
- flavone metabolic process [IDA]
- flavonoid biosynthetic process [IBA]
- flavonoid glucuronidation [IDA]
- heme catabolic process [TAS]
- heterocycle metabolic process [IC]
- negative regulation of catalytic activity [IDA]
- negative regulation of cellular glucuronidation [IDA]
- negative regulation of steroid metabolic process [IC]
- porphyrin-containing compound metabolic process [TAS]
- retinoic acid metabolic process [IC]
- small molecule metabolic process [TAS]
- steroid metabolic process [IC]
- xenobiotic glucuronidation [IDA]
- xenobiotic metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ESYT1
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Quantitative Score
- 0.375425428 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.375425427905888, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| UGT1A1 ESYT1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9362 | BioGRID | 3027936 |
Curated By
- BioGRID