BAIT
KLRK1
CD314, D12S2489E, KLR, NKG2-D, NKG2D
killer cell lectin-like receptor subfamily K, member 1
GO Process (6)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GPR56
BFPP, BPPR, TM7LN4, TM7XN1, UNQ540/PRO1083
G protein-coupled receptor 56
GO Process (13)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [TAS]
- Rho protein signal transduction [IDA]
- angiogenesis [IDA]
- brain development [IMP]
- cell-cell signaling [TAS]
- cerebral cortex radial glia guided migration [ISS]
- layer formation in cerebral cortex [ISS]
- negative regulation of cell proliferation [IDA]
- negative regulation of neuron migration [ISS]
- positive regulation of Rho protein signal transduction [ISS]
- positive regulation of cell adhesion [IDA]
- protein kinase C signaling [IDA]
- vascular endothelial growth factor production [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Status: Pre-Publication Dataset
Quantitative Score
- 0.480068208 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.480068207535844, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Curated By
- BioGRID