BAIT
WNT16
wingless-type MMTV integration site family, member 16
GO Process (12)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- Wnt signaling pathway [IBA]
- cell fate commitment [IBA]
- keratinocyte differentiation [IMP]
- keratinocyte proliferation [IMP]
- negative regulation of cell death [IMP]
- neuron differentiation [IBA]
- optic cup formation involved in camera-type eye development [ISS]
- oxidative stress-induced premature senescence [IMP]
- positive regulation of JNK cascade [IMP]
- positive regulation of gene expression [IMP]
- positive regulation of phosphatidylinositol 3-kinase signaling [IMP]
- replicative senescence [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
VWDE
von Willebrand factor D and EGF domains
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Status: Pre-Publication Dataset
Quantitative Score
- 0.432239499 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.432239499301045, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Curated By
- BioGRID